Odom68Lundsgaard's Profile

Country: Montserrat
Website: www.astrameds.com/
Signed Up: on July 18, 2018
Homepage: https://odom68lundsgaa...

 

<br /> In contrast, the median duration for patients receiving placebo was 0 min (range 0-23 min), and the mean duration was 3.9&plusmn;2.1 min (P &lt; 0.001; Figure 2a, c ). The proportion of treatment responders was 75% (12 patients) for those receiving Cenforce and 31% (five patients) for those receiving placebo (P &lt; 0.05). When VSS commenced 2 h after dosing, the median total duration of grade 3 or 4 erections for patients receiving Cenforce was 19.5 min (range 0-55 min), and the mean duration (&plusmn;s.e. mean) was 19.4&plusmn;4.1 min. A grade 3 or 4 erection was reported by 12 of 17 (71%) patients receiving Cenforce compared with 6 of 17 (35%) patients receiving placebo.
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<br /> The proportion of responders (patients with &gt;60% penile rigidity) was 82% (14 of 17 patients) after Cenforce treatment and 53% (9 of 17 patients) after placebo treatment. Seven patients had received previous treatments for ED: four received prostaglandin, two yohimbine and one an investigational drug. Patients' self-assessments of total mean durations of grade 3 and 4 erections were analysed using an analysis of variance (anova) model appropriate for a two-treatment, two-period crossover design (Study I). The duration of grade 3 or 4 erections (Study 2) was analysed using an anova model, with terms for sequence, patient, period and treatment.
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<br /> The time to onset of erections with &gt;60% rigidity (considered hard enough for penetrative sexual intercourse) at the base of the penis was calculated from the RigiScan&reg; data 14 The patients were asked to record all erections during VSS and to grade the degree of hardness on a scale of 1-4: grade 1 =an increase in penis size but not hardness; grade 2 =hard but not hard enough for penetration; grade 3 =hard enough for penetration but not completely hard; grade 4 =completely hard. Patients aged 35-70 years with a clinical diagnosis of ED of no known organic cause (as evidenced by the presence of nocturnal erections, erections of penetrative rigidity under any circumstance or a positive response to an intracavernosal prostaglandin E1 dose of ≤20 &micro;g or a papaverine dose of ≤40 mg) of at least 6 months' duration were included in the studies. Keywords: erectile dysfunction, Cenforce citrate, duration of action, onset of action.
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<br /> Study II: When VSS began 2 h postdose, the median duration of grade 3 or 4 erections was 19.5 min (0-55) for Cenforce vs 0 min (0-23) for placebo. Study II: The duration of grade 3 (hard enough for penetration) and grade 4 (fully hard) erections, determined by self-assessment during 60 min of VSS starting 2 and 4 h after Cenforce (100 mg) or placebo dosing, was measured in 16 patients.
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